Preheat the oven to 300 degrees F. Prep two baking sheets by placing a wire rack on the baking sheet.
Place the crackers in a 9x13 inch baking dish so they are against each other in an accordion-like manor - like you took them out of the packaging and lined them up in the dish (you may need to do two batches). This helps the butter and spices get over every bit of the crackers!
Melt the butter in a sauce pan over low heat. Stir in the sugar, garlic powder, paprika, pepper flakes, oregano, salt and pepper until combined. Pour the mixture over top of the crackers (again, you may need to do two batches!), trying to get in between each cracker. Use a spoon to drizzle any extra butter on the crackers and spread around the butter so it covers the crackers evenly.
Place the crackers in a single layer on the wire rack. Bake for 15 minutes, then flip and bake for 15 minutes more. Let cool completely before serving. You can keep these packaged in a resealable container or bag until you’re ready to use!